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Application of RNA Sequencing to identify transcriptome modification by DCLK1 in Colorectal Cancer Cells

Doublecortin like kinase 1 (DCLK1) is a cancer stem cell marker for the colorectal cancer (CRC). It plays critical roles in the oncogenesis, progression and metastasis of CRC. DCLK1 can be an intriguing therapeutic target for CRC treatment. However, the molecular mechanism of how DCLK1 functions is...

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Detalles Bibliográficos
Autores principales: Li, Lianna, Mei, Hao, Commey, Abednego Nii Adom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170768/
https://www.ncbi.nlm.nih.gov/pubmed/31636360
http://dx.doi.org/10.1038/s41417-019-0144-4