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Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging
Noninvasive bioluminescence imaging (BLI) of luciferase-expressing tumor cells has advanced pre-clinical evaluation of cancer therapies. Yet despite its successes, BLI is limited by poor spatial resolution and signal penetration, making it unusable for deep tissue or large animal imaging and prevent...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170803/ https://www.ncbi.nlm.nih.gov/pubmed/30674994 http://dx.doi.org/10.1038/s41417-019-0081-2 |