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Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging

Noninvasive bioluminescence imaging (BLI) of luciferase-expressing tumor cells has advanced pre-clinical evaluation of cancer therapies. Yet despite its successes, BLI is limited by poor spatial resolution and signal penetration, making it unusable for deep tissue or large animal imaging and prevent...

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Detalles Bibliográficos
Autores principales:	Vandergaast, Rianna, Khongwichit, Sarawut, Jiang, Huailei, DeGrado, Timothy R., Peng, Kah-Whye, Smith, Duncan R., Russell, Stephen J., Suksanpaisan, Lukkana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170803/ https://www.ncbi.nlm.nih.gov/pubmed/30674994 http://dx.doi.org/10.1038/s41417-019-0081-2

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