Improving Treatment Efficacy of In Situ Forming Implants via Concurrent Delivery of Chemotherapeutic and Chemosensitizer

P-glycoprotein (Pgp), a member of the ATP-binding cassette family, is one of the major causes of multidrug resistance in tumors. Current clinical treatments to overcome MDR involve the co-delivery of a Pgp inhibitor and a chemotherapeutic. A concern for this treatment that has led to varied clinical...

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Detalles Bibliográficos
Autores principales: Jeganathan, Selva, Budziszewski, Emily, Hernandez, Christopher, Dhingra, Anshul, Exner, Agata A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170888/
https://www.ncbi.nlm.nih.gov/pubmed/32313056
http://dx.doi.org/10.1038/s41598-020-63636-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170888/
https://www.ncbi.nlm.nih.gov/pubmed/32313056
http://dx.doi.org/10.1038/s41598-020-63636-x

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