Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression

Evidence suggests that fasting exerts extensive antitumor effects in various cancers, including colorectal cancer (CRC). However, the mechanism behind this response is unclear. We investigate the effect of fasting on glucose metabolism and malignancy in CRC. We find that fasting upregulates the expr...

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Detalles Bibliográficos
Autores principales: Weng, Mei-lin, Chen, Wan-kun, Chen, Xiang-yuan, Lu, Hong, Sun, Zhi-rong, Yu, Qi, Sun, Peng-fei, Xu, Ya-jun, Zhu, Min-min, Jiang, Nan, Zhang, Jin, Zhang, Jian-ping, Song, Yuan-lin, Ma, Duan, Zhang, Xiao-ping, Miao, Chang-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170903/
https://www.ncbi.nlm.nih.gov/pubmed/32313017
http://dx.doi.org/10.1038/s41467-020-15795-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170903/
https://www.ncbi.nlm.nih.gov/pubmed/32313017
http://dx.doi.org/10.1038/s41467-020-15795-8

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