The chloroalkaloid (−)-acutumine is biosynthesized via a Fe(II)- and 2-oxoglutarate-dependent halogenase in Menispermaceae plants

Plant halogenated natural products are rare and harbor various interesting bioactivities, yet the biochemical basis for the involved halogenation chemistry is unknown. While a handful of Fe(II)- and 2-oxoglutarate-dependent halogenases (2ODHs) have been found to catalyze regioselective halogenation...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Colin Y., Mitchell, Andrew J., Glinkerman, Christopher M., Li, Fu-Shuang, Pluskal, Tomáš, Weng, Jing-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170919/
https://www.ncbi.nlm.nih.gov/pubmed/32313070
http://dx.doi.org/10.1038/s41467-020-15777-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170919/
https://www.ncbi.nlm.nih.gov/pubmed/32313070
http://dx.doi.org/10.1038/s41467-020-15777-w

Ejemplares similares