Excessive folic acid supplementation in pregnant mice impairs insulin secretion and induces the expression of genes associated with fatty liver in their offspring

OBJECTIVE: Previous human and animal studies have shown that excessive maternal intake of folic acid (FA) predisposes to impaired glucose tolerance in the offspring. However, the underlying mechanism is unknown. Therefore, we aimed to determine whether excessive supplementation with FA during pregna...

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Detalles Bibliográficos
Autores principales: Kintaka, Yuri, Wada, Nobuhiro, Shioda, Seiji, Nakamura, Sadako, Yamazaki, Yuko, Mochizuki, Kazuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170958/
https://www.ncbi.nlm.nih.gov/pubmed/32322701
http://dx.doi.org/10.1016/j.heliyon.2020.e03597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170958/
https://www.ncbi.nlm.nih.gov/pubmed/32322701
http://dx.doi.org/10.1016/j.heliyon.2020.e03597

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