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Transcriptional and clonal characterization of B cell plasmablast diversity following primary and secondary natural DENV infection

Antibody-mediated humoral immunity is thought to play a central role in mediating the immunopathogenesis of acute DENV infection, but limited data are available on the diversity, specificity, and functionality of the antibody response at the molecular level elicited by primary or secondary DENV infe...

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Detalles Bibliográficos
Autores principales: Waickman, Adam T., Gromowski, Gregory D., Rutvisuttinunt, Wiriya, Li, Tao, Siegfried, Hayden, Victor, Kaitlin, Kuklis, Caitlin, Gomootsukavadee, Methee, McCracken, Michael K., Gabriel, Benjamin, Mathew, Anuja, Grinyo i Escuer, Ariadna, Fouch, Mallorie E., Liang, Jenny, Fernandez, Stefan, Davidson, Edgar, Doranz, Benjamin J., Srikiatkhachorn, Anon, Endy, Timothy, Thomas, Stephen J., Ellison, Damon, Rothman, Alan L., Jarman, Richard G., Currier, Jeffrey R., Friberg, Heather
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170960/
https://www.ncbi.nlm.nih.gov/pubmed/32315970
http://dx.doi.org/10.1016/j.ebiom.2020.102733