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Limits in the detection of m(6)A changes using MeRIP/m(6)A-seq
Many cellular mRNAs contain the modified base m(6)A, and recent studies have suggested that various stimuli can lead to changes in m(6)A. The most common method to map m(6)A and to predict changes in m(6)A between conditions is methylated RNA immunoprecipitation sequencing (MeRIP-seq), through which...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170965/ https://www.ncbi.nlm.nih.gov/pubmed/32313079 http://dx.doi.org/10.1038/s41598-020-63355-3 |