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Limits in the detection of m(6)A changes using MeRIP/m(6)A-seq

Many cellular mRNAs contain the modified base m(6)A, and recent studies have suggested that various stimuli can lead to changes in m(6)A. The most common method to map m(6)A and to predict changes in m(6)A between conditions is methylated RNA immunoprecipitation sequencing (MeRIP-seq), through which...

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Detalles Bibliográficos
Autores principales: McIntyre, Alexa B. R., Gokhale, Nandan S., Cerchietti, Leandro, Jaffrey, Samie R., Horner, Stacy M., Mason, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170965/
https://www.ncbi.nlm.nih.gov/pubmed/32313079
http://dx.doi.org/10.1038/s41598-020-63355-3