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Recapitulating kidney development in vitro by priming and differentiating mouse embryonic stem cells in monolayers

In order to harness the potential of pluripotent stem cells, we need to understand how to differentiate them to our target cell types. Here, we developed a protocol to differentiate mouse embryonic stem cells (ESCs) to renal progenitors in a step-wise manner. Microarrays were used to track the trans...

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Detalles Bibliográficos
Autores principales: Chow, Theresa, Wong, Frances T. M., Monetti, Claudio, Nagy, Andras, Cox, Brian, Rogers, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171095/
https://www.ncbi.nlm.nih.gov/pubmed/32351711
http://dx.doi.org/10.1038/s41536-020-0092-5