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Incorporating chemical sub-structures and protein evolutionary information for inferring drug-target interactions

Accumulating evidence has shown that drug-target interactions (DTIs) play a crucial role in the process of genomic drug discovery. Although biological experimental technology has made great progress, the identification of DTIs is still very time-consuming and expensive nowadays. Hence it is urgent t...

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Detalles Bibliográficos
Autores principales: Wang, Lei, You, Zhu-Hong, Li, Li-Ping, Yan, Xin, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171114/
https://www.ncbi.nlm.nih.gov/pubmed/32313024
http://dx.doi.org/10.1038/s41598-020-62891-2