Impacts of ciliary neurotrophic factor on the retinal transcriptome in a mouse model of photoreceptor degeneration

Ciliary neurotrophic factor (CNTF) has been tested in clinical trials for human retinal degeneration due to its potent neuroprotective effects in various animal models. To decipher CNTF-triggered molecular events in the degenerating retina, we performed high-throughput RNA sequencing analyses using...

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Detalles Bibliográficos
Autores principales: Wang, Yanjie, Rhee, Kun-Do, Pellegrini, Matteo, Yang, Xian-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171121/
https://www.ncbi.nlm.nih.gov/pubmed/32313077
http://dx.doi.org/10.1038/s41598-020-63519-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171121/
https://www.ncbi.nlm.nih.gov/pubmed/32313077
http://dx.doi.org/10.1038/s41598-020-63519-1

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