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Impacts of ciliary neurotrophic factor on the retinal transcriptome in a mouse model of photoreceptor degeneration
Ciliary neurotrophic factor (CNTF) has been tested in clinical trials for human retinal degeneration due to its potent neuroprotective effects in various animal models. To decipher CNTF-triggered molecular events in the degenerating retina, we performed high-throughput RNA sequencing analyses using...
Autores principales: | Wang, Yanjie, Rhee, Kun-Do, Pellegrini, Matteo, Yang, Xian-Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171121/ https://www.ncbi.nlm.nih.gov/pubmed/32313077 http://dx.doi.org/10.1038/s41598-020-63519-1 |
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