Inhibition of collagen XI alpha 1-induced fatty acid oxidation triggers apoptotic cell death in cisplatin-resistant ovarian cancer

Collagen type XI alpha 1 (COL11A1) is a novel biomarker associated with cisplatin resistance in ovarian cancer. However, the mechanisms underlying how COL11A1 confers cisplatin resistance in ovarian cancer are poorly understood. We identified that fatty acid β-oxidation (FAO) is upregulated by COL11...

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Detalles Bibliográficos
Autores principales: Nallanthighal, Sameera, Rada, Miran, Heiserman, James Patrick, Cha, Jennifer, Sage, Jessica, Zhou, Bo, Yang, Wei, Hu, Ye, Korgaonkar, Chaitali, Hanos, Christina Terpsithea, Ashkavand, Zahra, Norman, Kenneth, Orsulic, Sandra, Cheon, Dong-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171147/
https://www.ncbi.nlm.nih.gov/pubmed/32312965
http://dx.doi.org/10.1038/s41419-020-2442-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171147/
https://www.ncbi.nlm.nih.gov/pubmed/32312965
http://dx.doi.org/10.1038/s41419-020-2442-z

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