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Prostaglandin EP2 receptor downstream of Notch signaling inhibits differentiation of human skeletal muscle progenitors in differentiation conditions

Understanding the signaling pathways that regulate proliferation and differentiation of muscle progenitors is essential for successful cell transplantation for treatment of Duchenne muscular dystrophy. Here, we report that a γ-secretase inhibitor, DAPT (N-[N-(3,5-difluorophenacetyl-L-alanyl)]-S-phen...

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Detalles Bibliográficos
Autores principales: Sakai-Takemura, Fusako, Nogami, Ken’ichiro, Elhussieny, Ahmed, Kawabata, Kota, Maruyama, Yusuke, Hashimoto, Naohiro, Takeda, Shin’ichi, Miyagoe-Suzuki, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171165/
https://www.ncbi.nlm.nih.gov/pubmed/32313117
http://dx.doi.org/10.1038/s42003-020-0904-6