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Prostaglandin EP2 receptor downstream of Notch signaling inhibits differentiation of human skeletal muscle progenitors in differentiation conditions
Understanding the signaling pathways that regulate proliferation and differentiation of muscle progenitors is essential for successful cell transplantation for treatment of Duchenne muscular dystrophy. Here, we report that a γ-secretase inhibitor, DAPT (N-[N-(3,5-difluorophenacetyl-L-alanyl)]-S-phen...
Autores principales: | Sakai-Takemura, Fusako, Nogami, Ken’ichiro, Elhussieny, Ahmed, Kawabata, Kota, Maruyama, Yusuke, Hashimoto, Naohiro, Takeda, Shin’ichi, Miyagoe-Suzuki, Yuko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171165/ https://www.ncbi.nlm.nih.gov/pubmed/32313117 http://dx.doi.org/10.1038/s42003-020-0904-6 |
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