De Novo Purine Biosynthesis Is Required for Intracellular Growth of Staphylococcus aureus and for the Hypervirulence Phenotype of a purR Mutant

Staphylococcus aureus is a noted human and animal pathogen. Despite decades of research on this important bacterium, there are still many unanswered questions regarding the pathogenic mechanisms it uses to infect the mammalian host. This can be attributed to it possessing a plethora of virulence fac...

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Detalles Bibliográficos
Autores principales: Goncheva, Mariya I., Flannagan, Ronald S., Heinrichs, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171247/
https://www.ncbi.nlm.nih.gov/pubmed/32094249
http://dx.doi.org/10.1128/IAI.00104-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171247/
https://www.ncbi.nlm.nih.gov/pubmed/32094249
http://dx.doi.org/10.1128/IAI.00104-20

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