Leydig‐like cells derived from reprogrammed human foreskin fibroblasts by CRISPR/dCas9 increase the level of serum testosterone in castrated male rats

In the past few years, Leydig cell (LC) transplantation has been regarded as an effective strategy for providing physiological patterns of testosterone in vivo. Recently, we have successfully converted human foreskin fibroblasts (HFFs) into functional Leydig‐like cells (iLCs) in vitro by using the C...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Hua, Zhong, Liang, Zhou, Jin, Hou, Yanping, Zhang, Zhiyuan, Xing, Xiaoyu, Sun, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171312/
https://www.ncbi.nlm.nih.gov/pubmed/32160419
http://dx.doi.org/10.1111/jcmm.15018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171312/
https://www.ncbi.nlm.nih.gov/pubmed/32160419
http://dx.doi.org/10.1111/jcmm.15018

Ejemplares similares