Potent USP10/13 antagonist spautin‐1 suppresses melanoma growth via ROS‐mediated DNA damage and exhibits synergy with cisplatin

Malignant melanoma is one of the most invasive tumours. However, effective therapeutic strategies are limited, and overall survival rates remain low. By utilizing transcriptomic profiling, tissue array and molecular biology, we revealed that two key ubiquitin‐specific proteases (USPs), ubiquitin‐spe...

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Detalles Bibliográficos
Autores principales: Guo, Jia, Zhang, JiangLing, Liang, Long, Liu, Nian, Qi, Min, Zhao, Shuang, Su, Juan, Liu, Jing, Peng, Cong, Chen, Xiang, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171391/
https://www.ncbi.nlm.nih.gov/pubmed/32129945
http://dx.doi.org/10.1111/jcmm.15093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171391/
https://www.ncbi.nlm.nih.gov/pubmed/32129945
http://dx.doi.org/10.1111/jcmm.15093

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