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Induction of apoptosis through extrinsic/intrinsic pathways and suppression of ERK/NF‐κB signalling participate in anti‐glioblastoma of imipramine

Glioblastomas are the most aggressive type of brain tumour, with poor prognosis even after standard treatment such as surgical resection, temozolomide and radiation therapy. The overexpression of the nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐κB) in glioblastomas is recognize...

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Detalles Bibliográficos
Autores principales: Hsu, Fei-Ting, Chiang, I‐Tsang, Wang, Wei‐Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171418/
https://www.ncbi.nlm.nih.gov/pubmed/32149465
http://dx.doi.org/10.1111/jcmm.15022