Systemic Mastocytosis: Following the Tyrosine Kinase Inhibition Roadmap

Systemic mastocytosis is a rare and heterogeneous disease characterized by mast cell proliferation and activation. KIT is a transmembrane tyrosine kinase which plays a key role in mast cell growth, differentiation and survival. After interaction with its ligand, the stem cell factor, KIT dimerizes a...

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Detalles Bibliográficos
Autores principales: Piris-Villaespesa, Miguel, Alvarez-Twose, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171446/
https://www.ncbi.nlm.nih.gov/pubmed/32346366
http://dx.doi.org/10.3389/fphar.2020.00443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171446/
https://www.ncbi.nlm.nih.gov/pubmed/32346366
http://dx.doi.org/10.3389/fphar.2020.00443

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