Reversal of HER2 Negativity: An Unexpected Role for Lovastatin in Triple-Negative Breast Cancer Stem Cells

Effective treatment modality for triple-negative breast cancer (TNBC) is currently lacking due to the absence of defined receptor targets. Recently, we have demonstrated that lovastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor and a lipid-lowering drug, can selectively inhibit TN...

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Detalles Bibliográficos
Autores principales: Yi, Huimei, Wu, Mi, Zhang, Qiuting, Lu, Lu, Yao, Hui, Chen, Sisi, Li, Ying, Zheng, Chanjuan, He, Guangchun, Deng, Xiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Short Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171481/
https://www.ncbi.nlm.nih.gov/pubmed/32328175
http://dx.doi.org/10.7150/jca.39265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171481/
https://www.ncbi.nlm.nih.gov/pubmed/32328175
http://dx.doi.org/10.7150/jca.39265

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