Metformin in combination with JS-K inhibits growth of renal cell carcinoma cells via reactive oxygen species activation and inducing DNA breaks

Metformin (MET) is taken as a principal medication for remedying Type 2 diabetes mellitus. Its anti-tumor effect has been reported increasingly, but the precise mechanism of it remains unclear. This study aims to explore the efficacy of MET and MET combined with nitric oxide donor prodrug JS-K on th...

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Detalles Bibliográficos
Autores principales: Zhao, Yuwan, Luo, Qiuming, Mo, Jierong, Li, Jianwei, Ye, Dongcai, Ao, Zhixian, Chen, Lixin, Liu, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171495/
https://www.ncbi.nlm.nih.gov/pubmed/32328174
http://dx.doi.org/10.7150/jca.36372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171495/
https://www.ncbi.nlm.nih.gov/pubmed/32328174
http://dx.doi.org/10.7150/jca.36372

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