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Imaging hydroxyapatite in sub-retinal pigment epithelial deposits by fluorescence lifetime imaging microscopy with tetracycline staining

Significance: Recent evidence suggests that hydroxyapatite (HAP) in sub-retinal pigment epithelial (sub-RPE) deposits in aged human eyes may act to nucleate and contribute to their growth to clinically detectable size. Sub-RPE deposits such as drusen are clinical hallmarks of age-related macular deg...

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Detalles Bibliográficos
Autores principales: Szmacinski, Henryk, Hegde, Kavita, Zeng, Hui-Hui, Eslami, Katayoun, Puche, Adam C., Lengyel, Imre, Thompson, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171513/
https://www.ncbi.nlm.nih.gov/pubmed/32319262
http://dx.doi.org/10.1117/1.JBO.25.4.047001