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Protection of the transplant kidney during cold perfusion with doxycycline: proteomic analysis in a rat model

BACKGROUND: It has been previously shown that doxycycline (Doxy) protects the kidney from preservation injury by inhibition of matrix metalloproteinase. However, the precise molecular mechanism involved in this protection from injury is not known. We used a pharmaco-proteomics approach to identify p...

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Detalles Bibliográficos
Autores principales: Moser, Michael A. J., Sawicka, Katherine, Sawicka, Jolanta, Franczak, Aleksandra, Cohen, Alejandro, Bil-Lula, Iwona, Sawicki, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171734/
https://www.ncbi.nlm.nih.gov/pubmed/32336955
http://dx.doi.org/10.1186/s12953-020-00159-3