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Synthesis of new 2-amino-1,3,4-oxadiazole derivatives with anti-salmonella typhi activity evaluation

Reaction of phenyl acetic acid derivatives with thiosemicarbazide in the presence of POCl(3) afforded 5-(4-bromobenzyl)-1,3,4-oxadiazole-2-amine 1 and 5-(3-nitrophenyl)-1,3,4-oxadiazole -2-amine 2. Acylation of the amino group of oxadiazoles 1 and 2 with some acid chlorides such as methyl 4-(chloroc...

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Detalles Bibliográficos
Autor principal: Salama, Eid E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171753/
https://www.ncbi.nlm.nih.gov/pubmed/32337509
http://dx.doi.org/10.1186/s13065-020-00682-6