Low DLG2 gene expression, a link between 11q-deleted and MYCN-amplified neuroblastoma, causes forced cell cycle progression, and predicts poor patient survival

BACKGROUND: Neuroblastoma (NB) is a childhood neural crest tumor. There are two groups of aggressive NBs, one with MYCN amplification, and another with 11q chromosomal deletion; these chromosomal aberrations are generally mutually exclusive. The DLG2 gene resides in the 11q-deleted region, thus make...

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Detalles Bibliográficos
Autores principales: Keane, Simon, Améen, Sophie, Lindlöf, Angelica, Ejeskär, Katarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171851/
https://www.ncbi.nlm.nih.gov/pubmed/32312269
http://dx.doi.org/10.1186/s12964-020-00553-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171851/
https://www.ncbi.nlm.nih.gov/pubmed/32312269
http://dx.doi.org/10.1186/s12964-020-00553-6

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