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Human norovirus hyper-mutation revealed by ultra-deep sequencing

Human noroviruses (NoVs) are a major cause of gastroenteritis worldwide. It is thought that, similar to other RNA viruses, high mutation rates allow NoVs to evolve fast and to undergo rapid immune escape at the population level. However, the rate and spectrum of spontaneous mutations of human NoVs h...

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Detalles Bibliográficos
Autores principales: Cuevas, José M., Combe, Marine, Torres-Puente, Manoli, Garijo, Raquel, Guix, Susana, Buesa, Javier, Rodríguez-Díaz, Jesús, Sanjuán, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172324/
https://www.ncbi.nlm.nih.gov/pubmed/27094861
http://dx.doi.org/10.1016/j.meegid.2016.04.017