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Human norovirus hyper-mutation revealed by ultra-deep sequencing
Human noroviruses (NoVs) are a major cause of gastroenteritis worldwide. It is thought that, similar to other RNA viruses, high mutation rates allow NoVs to evolve fast and to undergo rapid immune escape at the population level. However, the rate and spectrum of spontaneous mutations of human NoVs h...
Autores principales: | Cuevas, José M., Combe, Marine, Torres-Puente, Manoli, Garijo, Raquel, Guix, Susana, Buesa, Javier, Rodríguez-Díaz, Jesús, Sanjuán, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172324/ https://www.ncbi.nlm.nih.gov/pubmed/27094861 http://dx.doi.org/10.1016/j.meegid.2016.04.017 |
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