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The Dm-Myb Oncoprotein Contributes to Insulator Function and Stabilizes Repressive H3K27me3 PcG Domains

Drosophila Myb (Dm-Myb) encodes a protein that plays a key role in regulation of mitotic phase genes. Here, we further refine its role in the context of a developing tissue as a potentiator of gene expression required for proper RNA polymerase II (RNA Pol II) function and efficient H3K4 methylation...

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Detalles Bibliográficos
Autores principales: Santana, Juan F., Parida, Mrutyunjaya, Long, Abby, Wankum, Joshua, Lilienthal, Anthony J., Nukala, Krishna M., Manak, J. Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172335/
https://www.ncbi.nlm.nih.gov/pubmed/32160531
http://dx.doi.org/10.1016/j.celrep.2020.02.053