Synthesis and testing of azaglutamine derivatives as inhibitors of Hepatitis A Virus (HAV) 3C proteinase

Hepatitis A virus (HAV) 3C proteinase is a picornaviral cysteine proteinase that is essential for cleavage of the initially synthesized viral polyprotein precursor to mature fragments and is therefore required for viral replication in vivo. Since the enzyme generally recognizes peptide substrates wi...

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Detalles Bibliográficos
Autores principales: Huang, Yanting, Malcolm, Bruce A, Vederas, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd. 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172622/
https://www.ncbi.nlm.nih.gov/pubmed/10353640
http://dx.doi.org/10.1016/S0968-0896(99)00006-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172622/
https://www.ncbi.nlm.nih.gov/pubmed/10353640
http://dx.doi.org/10.1016/S0968-0896(99)00006-1

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