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Viral proteases as targets for chemotherapeutic intervention

Many viruses encode proteinases that are essential for infectivity, and are consequently attractive chemotherapeutic targets. The biochemistry and structure of the human immunodeficiency virus proteinase have been characterized extensively, and potent peptide-mimetic inhibitors have been developed....

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Detalles Bibliográficos
Autores principales: Hellen, Christopher U.T., Wimmer, Eckard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172713/
https://www.ncbi.nlm.nih.gov/pubmed/1369416
http://dx.doi.org/10.1016/0958-1669(92)90010-G