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A picornaviral loop-to-loop replication complex

Picornaviruses replicate their RNA genomes through a highly conserved mechanism that involves an interaction between the principal viral protease (3C(pro)) and the 5′-UTR region of the viral genome. The 3C(pro) catalytic site is the target of numerous replication inhibitors. This paper describes the...

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Detalles Bibliográficos
Autores principales: Claridge, Jolyon K., Headey, Stephen J., Chow, John Y.H., Schwalbe, Martin, Edwards, Patrick J., Jeffries, Cy M., Venugopal, Hariprasad, Trewhella, Jill, Pascal, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172786/
https://www.ncbi.nlm.nih.gov/pubmed/19268541
http://dx.doi.org/10.1016/j.jsb.2009.02.010