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Synthesis and inhibitory properties of a thiomethylmercuric sialic acid with application to the X-ray structure determination of 9-O-acetylsialic acid esterase from influenza C virus
2-α-Thiomethylmercuryl 9-acetamido-9-deoxy-sialoside was prepared and found to inhibit the 9-O-acetylsialic acid esterase from influenza C virus in a competitive manner with a K(i) of 4.2±0.5 mM. The inhibitor is being used in the X-ray determination of the crystal structure of the esterase.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Published by Elsevier Ltd.
1996
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172942/ https://www.ncbi.nlm.nih.gov/pubmed/8879557 http://dx.doi.org/10.1016/0968-0896(96)00123-X |