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STING modulators: Predictive significance in drug discovery

Cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS) — stimulator of interferon genes (STING) signaling pathway plays the critical role in the immune response to DNA. Pharmacological modulation of the STING pathway has been well characterized both from structural and functional per...

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Detalles Bibliográficos
Autores principales: Cui, Xiangling, Zhang, Rongyu, Cen, Shan, Zhou, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Masson SAS. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172983/
https://www.ncbi.nlm.nih.gov/pubmed/31419779
http://dx.doi.org/10.1016/j.ejmech.2019.111591