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STING modulators: Predictive significance in drug discovery
Cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS) — stimulator of interferon genes (STING) signaling pathway plays the critical role in the immune response to DNA. Pharmacological modulation of the STING pathway has been well characterized both from structural and functional per...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Masson SAS.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172983/ https://www.ncbi.nlm.nih.gov/pubmed/31419779 http://dx.doi.org/10.1016/j.ejmech.2019.111591 |