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Genetic analysis of heptad-repeat regions in the G2 fusion subunit of the Junín arenavirus envelope glycoprotein

The G2 fusion subunit of the Junín virus envelope glycoprotein GP-C contains two hydrophobic heptad-repeat regions that are postulated to form a six-helix bundle structure required for the membrane fusion activity of Class I viral fusion proteins. We have investigated the role of these heptad-repeat...

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Detalles Bibliográficos
Autores principales: York, Joanne, Agnihothram, Sudhakar S., Romanowski, Victor, Nunberg, Jack H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173107/
https://www.ncbi.nlm.nih.gov/pubmed/16169032
http://dx.doi.org/10.1016/j.virol.2005.08.030