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Lethal murine infection model for human respiratory disease-associated Pteropine orthoreovirus

Pteropine orthoreovirus (PRV) is an emerging bat-borne human pathogen causing severe respiratory illness. To date, however, the evaluation of PRV virulence has largely depended on the limited numbers of clinical cases owing to the lack of animal models. To develop an in vivo model of PRV infection,...

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Detalles Bibliográficos
Autores principales: Kanai, Yuta, Kawagishi, Takahiro, Okamoto, Minoru, Sakai, Yusuke, Matsuura, Yoshiharu, Kobayashi, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173163/
https://www.ncbi.nlm.nih.gov/pubmed/29128757
http://dx.doi.org/10.1016/j.virol.2017.10.021