Nonhomologous RNA Recombination in a Cell-Free System: Evidence for a Transesterification Mechanism Guided by Secondary Structure

Extensive nonhomologous recombinations occur between the 5′ and 3′ fragments of a replicable RNA in a cell-free system composed of pure Qβ phage replicase and ribonucleoside triphosphates, providing direct evidence for the ability of RNAs to recombine without DNA intermediates and in the absence of...

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Detalles Bibliográficos
Autores principales: Chetverin, Alexander B, Chetverina, Helena V, Demidenko, Alexander A, Ugarov, Victor I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press. 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173214/
https://www.ncbi.nlm.nih.gov/pubmed/9038341
http://dx.doi.org/10.1016/S0092-8674(00)81890-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173214/
https://www.ncbi.nlm.nih.gov/pubmed/9038341
http://dx.doi.org/10.1016/S0092-8674(00)81890-5

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