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Nonhomologous RNA Recombination in a Cell-Free System: Evidence for a Transesterification Mechanism Guided by Secondary Structure
Extensive nonhomologous recombinations occur between the 5′ and 3′ fragments of a replicable RNA in a cell-free system composed of pure Qβ phage replicase and ribonucleoside triphosphates, providing direct evidence for the ability of RNAs to recombine without DNA intermediates and in the absence of...
Autores principales: | Chetverin, Alexander B, Chetverina, Helena V, Demidenko, Alexander A, Ugarov, Victor I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press.
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173214/ https://www.ncbi.nlm.nih.gov/pubmed/9038341 http://dx.doi.org/10.1016/S0092-8674(00)81890-5 |
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