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What are the pros and cons of the use of host-targeted agents against hepatitis C?

Hepatitis C virus (HCV) therapy is living a revolution. Host-targeted agents (HTAs) block HCV production by interacting with host cell components. Because they target conserved host proteins, not variable viral proteins, HTAs have the potential for pangenotypic antiviral activity and a high barrier...

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Detalles Bibliográficos
Autor principal: Pawlotsky, Jean-Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173253/
https://www.ncbi.nlm.nih.gov/pubmed/24583032
http://dx.doi.org/10.1016/j.antiviral.2014.02.008