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What are the pros and cons of the use of host-targeted agents against hepatitis C?
Hepatitis C virus (HCV) therapy is living a revolution. Host-targeted agents (HTAs) block HCV production by interacting with host cell components. Because they target conserved host proteins, not variable viral proteins, HTAs have the potential for pangenotypic antiviral activity and a high barrier...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier B.V.
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173253/ https://www.ncbi.nlm.nih.gov/pubmed/24583032 http://dx.doi.org/10.1016/j.antiviral.2014.02.008 |