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Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

In cells treated with brefeldin A (BFA), movement of newly synthesized membrane proteins from the endoplasmic reticulum (ER) to the Golgi apparatus was blocked. Surprisingly, the glycoproteins retained in the ER were rapidly processed by cis/medial Golgi enzymes but not by trans Golgi enzymes. An ex...

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Detalles Bibliográficos
Autores principales: Lippincott-Schwartz, Jennifer, Yuan, Lydia C., Bonifacino, Juan S., Klausner, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173269/
https://www.ncbi.nlm.nih.gov/pubmed/2647301
http://dx.doi.org/10.1016/0092-8674(89)90685-5