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Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER
In cells treated with brefeldin A (BFA), movement of newly synthesized membrane proteins from the endoplasmic reticulum (ER) to the Golgi apparatus was blocked. Surprisingly, the glycoproteins retained in the ER were rapidly processed by cis/medial Golgi enzymes but not by trans Golgi enzymes. An ex...
Autores principales: | Lippincott-Schwartz, Jennifer, Yuan, Lydia C., Bonifacino, Juan S., Klausner, Richard D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
1989
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173269/ https://www.ncbi.nlm.nih.gov/pubmed/2647301 http://dx.doi.org/10.1016/0092-8674(89)90685-5 |
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