JAK2 and Beyond: JAK2V617 Mutational Study of Myeloproliferative Disorders and Haematological Malignancies

BACKGROUND: Janus Tyrosine Kinase-2 (JAK2 V617F), a novel point mutation affecting the MPD’S is a somatic gain-of-function mutation. It alters a highly conserved amino acid valine in the negative regulatory JH2 domain to phenylalanine predicted to dysregulate kinase activity. AIM: To evaluate the pr...

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Detalles Bibliográficos
Autor principal: Syeed, Nidda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173381/
https://www.ncbi.nlm.nih.gov/pubmed/31870101
http://dx.doi.org/10.31557/APJCP.2019.20.12.3611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173381/
https://www.ncbi.nlm.nih.gov/pubmed/31870101
http://dx.doi.org/10.31557/APJCP.2019.20.12.3611

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