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Polymer-Stabilized Sialylated Nanoparticles: Synthesis, Optimization, and Differential Binding to Influenza Hemagglutinins

[Image: see text] During influenza infection, hemagglutinins (HAs) on the viral surface bind to sialic acids on the host cell’s surface. While all HAs bind sialic acids, human influenza targets terminal α2,6 sialic acids and avian influenza targets α2,3 sialic acids. For interspecies transmission (z...

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Detalles Bibliográficos
Autores principales: Richards, Sarah-Jane, Baker, Alexander N., Walker, Marc, Gibson, Matthew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173702/
https://www.ncbi.nlm.nih.gov/pubmed/32191036
http://dx.doi.org/10.1021/acs.biomac.0c00179