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Admixture mapping identifies genetic regions associated with blood pressure phenotypes in African Americans

Hypertension occurs at a higher rate in African Americans than in European Americans. Based on the assumption that causal variants are more frequently found on DNA segments inherited from the ancestral population with higher disease risk, we employed admixture mapping to identify genetic loci with e...

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Detalles Bibliográficos
Autores principales: Liu, Zhi, Shriner, Daniel, Hansen, Nancy F., Rotimi, Charles N., Mullikin, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173845/
https://www.ncbi.nlm.nih.gov/pubmed/32315356
http://dx.doi.org/10.1371/journal.pone.0232048