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Inhibition of myostatin prevents microgravity-induced loss of skeletal muscle mass and strength

The microgravity conditions of prolonged spaceflight are known to result in skeletal muscle atrophy that leads to diminished functional performance. To assess if inhibition of the growth factor myostatin has potential to reverse these effects, mice were treated with a myostatin antibody while housed...

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Detalles Bibliográficos
Autores principales: Smith, Rosamund C., Cramer, Martin S., Mitchell, Pamela J., Lucchesi, Jonathan, Ortega, Alicia M., Livingston, Eric W., Ballard, Darryl, Zhang, Ling, Hanson, Jeff, Barton, Kenneth, Berens, Shawn, Credille, Kelly M., Bateman, Ted A., Ferguson, Virginia L., Ma, Yanfei L., Stodieck, Louis S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173869/
https://www.ncbi.nlm.nih.gov/pubmed/32315311
http://dx.doi.org/10.1371/journal.pone.0230818