Cargando…
Inhibition of myostatin prevents microgravity-induced loss of skeletal muscle mass and strength
The microgravity conditions of prolonged spaceflight are known to result in skeletal muscle atrophy that leads to diminished functional performance. To assess if inhibition of the growth factor myostatin has potential to reverse these effects, mice were treated with a myostatin antibody while housed...
Autores principales: | Smith, Rosamund C., Cramer, Martin S., Mitchell, Pamela J., Lucchesi, Jonathan, Ortega, Alicia M., Livingston, Eric W., Ballard, Darryl, Zhang, Ling, Hanson, Jeff, Barton, Kenneth, Berens, Shawn, Credille, Kelly M., Bateman, Ted A., Ferguson, Virginia L., Ma, Yanfei L., Stodieck, Louis S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173869/ https://www.ncbi.nlm.nih.gov/pubmed/32315311 http://dx.doi.org/10.1371/journal.pone.0230818 |
Ejemplares similares
-
Inhibiting myostatin signaling partially mitigates structural and functional adaptations to hindlimb suspension in mice
por: Hanson, Andrea M., et al.
Publicado: (2023) -
Myostatin inhibitors as therapies for muscle wasting associated with cancer and other disorders
por: Smith, Rosamund C., et al.
Publicado: (2013) -
Myostatin in the Pathophysiology of Skeletal Muscle
por: Carnac, Gilles, et al.
Publicado: (2007) -
Myostatin: A Skeletal Muscle Chalone
por: Lee, Se-Jin
Publicado: (2023) -
Deciphering Myostatin’s Regulatory, Metabolic, and Developmental Influence in Skeletal Diseases
por: Omosule, Catherine L., et al.
Publicado: (2021)