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Multimeric single-domain antibody complexes protect against bunyavirus infections

The World Health Organization has included three bunyaviruses posing an increasing threat to human health on the Blueprint list of viruses likely to cause major epidemics and for which no, or insufficient countermeasures exist. Here, we describe a broadly applicable strategy, based on llama-derived...

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Detalles Bibliográficos
Autores principales: Wichgers Schreur, Paul J, van de Water, Sandra, Harmsen, Michiel, Bermúdez-Méndez, Erick, Drabek, Dubravka, Grosveld, Frank, Wernike, Kerstin, Beer, Martin, Aebischer, Andrea, Daramola, Olalekan, Rodriguez Conde, Sara, Brennan, Karen, Kozub, Dorota, Søndergaard Kristiansen, Maiken, Mistry, Kieran K, Deng, Ziyan, Hellert, Jan, Guardado-Calvo, Pablo, Rey, Félix A, van Keulen, Lucien, Kortekaas, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173960/
https://www.ncbi.nlm.nih.gov/pubmed/32314955
http://dx.doi.org/10.7554/eLife.52716