Dual orexin and MCH neuron-ablated mice display severe sleep attacks and cataplexy

Orexin/hypocretin-producing and melanin-concentrating hormone-producing (MCH) neurons are co-extensive in the hypothalamus and project throughout the brain to regulate sleep/wakefulness. Ablation of orexin neurons decreases wakefulness and results in a narcolepsy-like phenotype, whereas ablation of...

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Detalles Bibliográficos
Autores principales: Hung, Chi Jung, Ono, Daisuke, Kilduff, Thomas S, Yamanaka, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173968/
https://www.ncbi.nlm.nih.gov/pubmed/32314734
http://dx.doi.org/10.7554/eLife.54275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173968/
https://www.ncbi.nlm.nih.gov/pubmed/32314734
http://dx.doi.org/10.7554/eLife.54275

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